Methyl 4-((dimethoxyphosphoryl)methyl)benzoate

Methyl 4-((dimethoxyphosphoryl)methyl)benzoate - Names and Identifiers

Name	4-(Dimethoxy-phosphorylmethyl)-benzoic acid methyl ester
Synonyms	Methyl 4-((dimethoxyphosphoryl)methyl)benzoate 4-(Dimethoxy-phosphorylmethyl)-benzoic acid methyl ester Benzoic acid, 4-[(dimethoxyphosphinyl)methyl]-, methyl ester
CAS	78022-19-2

Methyl 4-((dimethoxyphosphoryl)methyl)benzoate - Physico-chemical Properties

Molecular Formula	C11H15O5P
Molar Mass	258.21
Density	1.209±0.06 g/cm3(Predicted)
Boling Point	184 °C(Press: 0.533 Torr)

Methyl 4-((dimethoxyphosphoryl)methyl)benzoate - Introduction

4-(Dimethoxy-phosphorylmethyl)-benzoic acid ester is an organic compound. The following is an introduction to its nature, use, preparation and safety information:

Nature:
-Appearance: 4-(Dimethoxy-phosphorylmethyl)-benzoic acid methyl ester is a colorless to pale yellow liquid.
-Melting point: about -45 ℃.
-Boiling point: about 210 ℃.
-Molecular formula: C11H15O5P.
-Molecular weight: about 270.2g/mol.

Use:
- 4-(Dimethoxy-phosphorylmethyl)-benzoic acid methyl ester is mainly used as an intermediate for plant growth regulators and pesticides.
-It can also be used as a light stabilizer, a synthetic intermediate for photosensitive compounds, and is used in the fields of organic synthesis and pharmaceutical research.

Preparation Method:
The preparation of 4-(Dimethoxy-phosphorylmethyl)-benzoic acid ester can be completed by the following steps:
1. First, benzoic acid is reacted with methine sulfoxide to obtain methine sulfoxide benzoate.
2. Then, the benzoic acid methine sulfoxide ester is reacted with trimethylphosphoryl chloride to generate 4-((dimethylphosphoryl) methyl) benzoic acid.
3. Finally, 4-((dimethylphosphoryl) methyl) benzoic acid is reacted with methanol to generate 4-(Dimethoxy-phosphorylmethyl)-benzoic acid ester.

Safety Information:
- 4-(Dimethoxy-phosphorylmethyl)-benzoic acid methyl ester has low toxicity under general conditions, it still needs to be used carefully.
-Contact with skin and eyes may cause irritation and should be avoided.
-Inhalation or ingestion may cause gastrointestinal irritation, vomiting and lung damage. If inhaled or ingested accidentally, seek medical attention.
-Pay attention to fire prevention and ventilation during operation and storage.

Last Update：2024-04-09 21:01:54